Curious Kids: How does DNA affect our fingerprints and eye colour?


PTI, Feb 13, 2023, 11:52 AM IST

Solving crimes in real life is not quite like it is on television, but in both settings, evidence is required. Fingerprints and DNA left at a crime scene are both excellent sources of evidence.

Deoxyribonucleic acid (DNA) has some influence on our fingertips, but what really makes fingerprints unique is the special folding pattern of tiny ridges on our skin. This occurs during fetal development and gives humans the ability to hold and grip objects. No two patterns of ridges are exactly alike.

DNA fingerprinting, on the other hand, is another way of collecting evidence that enables investigators to narrow down the identity of an individual based on unique genetic patterns.

A set of instructions

DNA is the genetic information contained inside each of our cells that makes us who we are. DNA acts like a set of instructions written in a special code using just four letters: A-adenine, T-thymine, C-cytosine, and G-guanine. These letters refer to nucleotides, and it is the specific order of nucleotides within DNA that represents the instructions for all the cells and their functions in our body.

The complete set of DNA instructions is 99.9 per cent similar across every single human on the planet — but the tiny fraction that is different is as unique as the prints on the tips of your fingers.

These unique regions occur at known positions in our DNA in small sections called microsatellites, or tandem repeats. Microsatellites contain short segments of repeating DNA that are typically one to six nucleotides long (for example, GATGATGAT). Everyone has the same microsatellites in the same known positions in our DNA, however, the number of repeats varies from person to person.

You may have “GAT” repeated 10 times, whereas your teacher may have “GAT” repeating 12 times. As a result of these differences in the number of repeats, microsatellites have easily measurable lengths and investigators can use these measurements to generate a match between a suspect’s DNA and a crime scene sample.

Determining appearance from DNA

DNA fingerprinting may not always produce a match, or investigators may not have any suspects to compare crime scene DNA to. So how do investigators know who to look for? New methods are using DNA left at a crime scene to teach us about what a suspect looks like.

It might sound like science fiction, but a new technique called forensic DNA phenotyping (FDP) can help generate a suspect profile from the genetic material left at a crime scene. Using FDP, investigators can determine an individual’s age, ancestry, hair colour, skin colour and eye colour.

Let’s use eye colour as an example. The colour of your eyes is dependent on how much eumelanin you have in the iris. Eumelanin is a dark brownish-black pigment, and it absorbs a large amount of light. Individuals who have a lot of eumelanin in their irises have eye colours that appear dark, such as brown.

There are several genes responsible for controlling eumelanin production in the eye, but one of the most important genes for eye colour is called OCA2, located on chromosome 15.

Here is where our DNA instruction book comes in handy again. At any given position in our DNA sequence, we have two nucleotides, one on the chromosome inherited from our mother and one on the chromosome from our father. Individuals with two copies of “G” at a specific position near OCA2 (inheriting one “G” from their mother and another “G” from their father) produce less eumelanin and are more likely to have blue eyes.

In contrast, individuals with one or two copies of an “A” at the same position produce more eumelanin and are more likely to have brown eyes. Researchers are working to improve FDP technology every day, as individuals with intermediate eye colours such as green and hazel are very hard to determine.

However, the ability to determine if crime scene DNA came from an individual with blue or brown eyes might be the information an investigator needs to narrow down a group of suspects.

By Cristina Abbatangelo, PhD Student, Anthropology, University of Toronto (The Conversation)

Udayavani is now on Telegram. Click here to join our channel and stay updated with the latest news.

Top News

Actress Kasthuri released from jail, says ‘I thank those who made me raging storm’

Kidnapped for ransom in 1998, 26/11 survivor Gautam Adani faces biggest trial

100 engineering colleges in Karnataka to be ‘adopted’ by corporates by next year: IT Minister Kharge

Siddaramaiah defends BPL ration card cancellation, says only ineligible beneficiaries affected

China announces new policy measures to protect its exports from Trump’s new tariff threat

Renovated Medical Oncology OPD and Chemotherapy Day Care Centre inaugurated at Kasturba Hospital, Manipal

Karnataka Health Minister justifies revision of user fees in state-run hospitals

Related Articles More

BTS2024: If India can make rocket sensors, it can also make car sensors, says ISRO chief Somanath

World COPD Day: Know your lung function

SpaceX successfully launches ISRO’s 4,700 kg communication satellite from US

As AI and megaplatforms take over, the hyperlinks that built the web may face extinction

Plastic waste could double by 2050, researchers find, suggest policies to address issue

MUST WATCH

Christmas Cake Fruit Mixing

DK Shivakumar

Rose Cultivation

Geethotsava

Naxal Operation


Latest Additions

Siddaramaiah says confident of winning all three bypolls in Karnataka

Hop on! IT Minister Priyank Kharge checks out Uber Shuttle at Bengaluru Tech Summit

Actress Kasthuri released from jail, says ‘I thank those who made me raging storm’

Kidnapped for ransom in 1998, 26/11 survivor Gautam Adani faces biggest trial

AIMPLB to hold its annual general sessions in Bengaluru from November 23

Thanks for visiting Udayavani

You seem to have an Ad Blocker on.
To continue reading, please turn it off or whitelist Udayavani.